Minisatellite instability in severe combined immunodeficiency mouse cells

We have recently found that okadaic acid, which shows strong inhibitory activity on protein serine/threonine phosphatases and tumor-promoting activity in vivo and in vitro, induces minisatellite mutation (MSM). Human tumors and chemically induced counterparts in experimental animals are also sometim...

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Bibliographic Details
Main Authors: Imai, Hiroshi, Nakagama, Hitoshi, Komatsu, Kenshi, Shiraishi, Taizo, Fukuda, Hirokazu, Sugimura, Takashi, Nagao, Minako
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC23497/
https://ncbi.nlm.nih.gov/pubmed/9380717
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