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Induction of minisatellite mutation in NIH 3T3 cells by treatment with the tumor promoter okadaic acid
Okadaic acid (OA) is a strong tumor promoter of mouse skin carcinogenesis and also a potent inhibitor of serine/threonine protein phosphatases. OA induces various genetic alterations in cultured cells, such as diphtheria-toxin-resistance mutations, sister chromatid exchange, exclusion of exogenous t...
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Autori principali: | , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
The National Academy of Sciences of the USA
1997
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23496/ https://ncbi.nlm.nih.gov/pubmed/9380716 |
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