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Induction of minisatellite mutation in NIH 3T3 cells by treatment with the tumor promoter okadaic acid

Okadaic acid (OA) is a strong tumor promoter of mouse skin carcinogenesis and also a potent inhibitor of serine/threonine protein phosphatases. OA induces various genetic alterations in cultured cells, such as diphtheria-toxin-resistance mutations, sister chromatid exchange, exclusion of exogenous t...

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Autori principali: Nakagama, Hitoshi, Kaneko, Shigeto, Shima, Hiroshi, Inamori, Hideaki, Fukuda, Hirokazu, Kominami, Ryo, Sugimura, Takashi, Nagao, Minako
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC23496/
https://ncbi.nlm.nih.gov/pubmed/9380716
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