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Unfolding of quadruplex structure in the G-rich strand of the minisatellite repeat by the binding protein UP1

The mouse hypervariable minisatellite (MN) Pc-1 consists of tandem repeats of d(GGCAG) and flanked sequences. We have previously demonstrated that single-stranded d(GGCAG)(n) folds into the intramolecular folded-back quadruplex structure under physiological conditions. Because DNA polymerase progres...

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Detalhes bibliográficos
Main Authors: Fukuda, Hirokazu, Katahira, Masato, Tsuchiya, Naoto, Enokizono, Yoshiaki, Sugimura, Takashi, Nagao, Minako, Nakagama, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130521/
https://ncbi.nlm.nih.gov/pubmed/12235355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152456899
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