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Induction of minisatellite mutation in NIH 3T3 cells by treatment with the tumor promoter okadaic acid

Okadaic acid (OA) is a strong tumor promoter of mouse skin carcinogenesis and also a potent inhibitor of serine/threonine protein phosphatases. OA induces various genetic alterations in cultured cells, such as diphtheria-toxin-resistance mutations, sister chromatid exchange, exclusion of exogenous t...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Nakagama, Hitoshi, Kaneko, Shigeto, Shima, Hiroshi, Inamori, Hideaki, Fukuda, Hirokazu, Kominami, Ryo, Sugimura, Takashi, Nagao, Minako
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23496/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.10813
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