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NEDD4L Overexpression Rescues the Release and Infectivity of Human Immunodeficiency Virus Type 1 Constructs Lacking PTAP and YPXL Late Domains

The cellular ESCRT pathway functions in membrane remodeling events that accompany endosomal protein sorting, cytokinesis, and enveloped RNA virus budding. In the last case, short sequence motifs (termed late domains) within human immunodeficiency virus type 1 (HIV-1) p6(Gag) bind and recruit two ESC...

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Autors principals: Chung, Hyo-Young, Morita, Eiji, von Schwedler, Uta, Müller, Barbara, Kräusslich, Hans-Georg, Sundquist, Wesley I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346761/
https://ncbi.nlm.nih.gov/pubmed/18321968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02667-07
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