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Efficient and Specific Rescue of Human Immunodeficiency Virus Type 1 Budding Defects by a Nedd4-Like Ubiquitin Ligase

To exit infected cells, human immunodeficiency virus type 1 (HIV-1) exploits the vacuolar protein-sorting pathway by engaging Tsg101 and ALIX through PTAP and LYPx(n)L late assembly (L) domains. In contrast, less-complex retroviruses often use PPxY L domains to recruit Nedd4 family ubiquitin ligases...

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Detalhes bibliográficos
Main Authors: Usami, Yoshiko, Popov, Sergei, Popova, Elena, Göttlinger, Heinrich G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346742/
https://ncbi.nlm.nih.gov/pubmed/18321969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02675-07
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