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Divergent Bro1 Domains Share the Capacity To Bind Human Immunodeficiency Virus Type 1 Nucleocapsid and To Enhance Virus-Like Particle Production

To promote the release of infectious virions, human immunodeficiency virus type 1 (HIV-1) exploits the endosomal sorting complex required for transport (ESCRT) pathway by engaging Tsg101 and ALIX through late assembly (L) domains in p6 Gag. An LYPx(n)L motif in p6 serves as docking site for the cent...

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Detalhes bibliográficos
Main Authors: Popov, Sergei, Popova, Elena, Inoue, Michio, Göttlinger, Heinrich G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704772/
https://ncbi.nlm.nih.gov/pubmed/19403673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00198-09
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