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Murine Model for Assessment of Plasmodium falciparum Transmission-Blocking Vaccine Using Transgenic Plasmodium berghei Parasites Expressing the Target Antigen Pfs25

Currently, there is no animal model for Plasmodium falciparum challenge to evaluate malaria transmission-blocking vaccines based on the well-established Pfs25 target antigen. The biological activity of transmission-blocking antibodies is typically assessed using an assay known as the membrane feedin...

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Detalhes bibliográficos
Main Authors: Mlambo, Godfree, Maciel, Jorge, Kumar, Nirbhay
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346707/
https://ncbi.nlm.nih.gov/pubmed/18316385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01409-07
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