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Aberrant Sporogonic Development of Dmc1 (a Meiotic Recombinase) Deficient Plasmodium berghei Parasites

BACKGROUND: In Plasmodium, meiosis occurs in diploid zygotes as they develop into haploid motile ookinetes inside the mosquito. Further sporogonic development involves transformation of ookinetes into oocysts and formation of infective sporozoites. METHODOLOGY/PRINCIPAL FINDINGS: Reverse genetics wa...

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Detalhes bibliográficos
Main Authors: Mlambo, Godfree, Coppens, Isabelle, Kumar, Nirbhay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528682/
https://ncbi.nlm.nih.gov/pubmed/23285059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052480
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