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Effect of CpG Oligodeoxynucleotides on the Immunogenicity of Pfs25, a Plasmodium falciparum Transmission-Blocking Vaccine Antigen

Antibodies directed against Pfs25, a protein present on the surface of zygotes and ookinetes of Plasmodium falciparum, completely block pathogen transmission. We evaluated the immunomodulatory effect of CpG oligodeoxynucleotides (ODN) on the immunogenicity of recombinant Pfs25 (rPfs25) formulated in...

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Bibliographische Detailangaben
Hauptverfasser: Coban, Cevayir, Ishii, Ken J., Stowers, Anthony W., Keister, David B., Klinman, Dennis M., Kumar, Nirbhay
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC344005/
https://ncbi.nlm.nih.gov/pubmed/14688140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.584-588.2004
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