Effect of CpG Oligodeoxynucleotides on the Immunogenicity of Pfs25, a Plasmodium falciparum Transmission-Blocking Vaccine Antigen

Antibodies directed against Pfs25, a protein present on the surface of zygotes and ookinetes of Plasmodium falciparum, completely block pathogen transmission. We evaluated the immunomodulatory effect of CpG oligodeoxynucleotides (ODN) on the immunogenicity of recombinant Pfs25 (rPfs25) formulated in...

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Autors principals: Coban, Cevayir, Ishii, Ken J., Stowers, Anthony W., Keister, David B., Klinman, Dennis M., Kumar, Nirbhay
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC344005/
https://ncbi.nlm.nih.gov/pubmed/14688140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.1.584-588.2004
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