Iminosugars in Combination with Interferon and Ribavirin Permanently Eradicate Noncytopathic Bovine Viral Diarrhea Virus from Persistently Infected Cells

We evaluated interferon (IFN) and ribavirin (RBV) as dual therapy and as part of triple-combination therapies with the iminosugars N-butyl-deoxynojirimycin (NB-DNJ), N-nonyl-deoxynojirimycin, and N-7-oxanonyl-6-deoxymethyl-galactonojirimycin. The ability of these compounds to clear bovine viral diar...

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Detalhes bibliográficos
Main Authors: Woodhouse, Stephen D., Smith, Caroline, Michelet, Maud, Branza-Nichita, Norica, Hussey, Mark, Dwek, Raymond A., Zitzmann, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346636/
https://ncbi.nlm.nih.gov/pubmed/18316522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01181-07
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