An Inducible and Reversible Mouse Genetic Rescue System

Inducible and reversible regulation of gene expression is a powerful approach for uncovering gene function. We have established a general method to efficiently produce reversible and inducible gene knockout and rescue in mice. In this system, which we named iKO, the target gene can be turned on and...

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Detalhes bibliográficos
Main Authors: Zeng, Hongkui, Horie, Kyoji, Madisen, Linda, Pavlova, Maria N., Gragerova, Galina, Rohde, Alex D., Schimpf, Brian A., Liang, Yuqiong, Ojala, Ethan, Kramer, Farah, Roth, Patricia, Slobodskaya, Olga, Dolka, Io, Southon, Eileen A., Tessarollo, Lino, Bornfeldt, Karin E., Gragerov, Alexander, Pavlakis, George N., Gaitanaris, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346557/
https://ncbi.nlm.nih.gov/pubmed/18464897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000069
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