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The Impact of Recombination on Nucleotide Substitutions in the Human Genome

Unraveling the evolutionary forces responsible for variations of neutral substitution patterns among taxa or along genomes is a major issue for detecting selection within sequences. Mammalian genomes show large-scale regional variations of GC-content (the isochores), but the substitution processes a...

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Detalhes bibliográficos
Main Authors: Duret, Laurent, Arndt, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346554/
https://ncbi.nlm.nih.gov/pubmed/18464896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000071
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