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The red queen model of recombination hotspots evolution in the light of archaic and modern human genomes.

Recombination is an essential process in eukaryotes, which increases diversity by disrupting genetic linkage between loci and ensures the proper segregation of chromosomes during meiosis. In the human genome, recombination events are clustered in hotspots, whose location is determined by the PRDM9 p...

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Detalhes bibliográficos
Main Authors: Yann Lesecque, Sylvain Glémin, Nicolas Lartillot, Dominique Mouchiroud, Laurent Duret
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-11-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC4230742?pdf=render
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