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The Red Queen Model of Recombination Hotspots Evolution in the Light of Archaic and Modern Human Genomes

Recombination is an essential process in eukaryotes, which increases diversity by disrupting genetic linkage between loci and ensures the proper segregation of chromosomes during meiosis. In the human genome, recombination events are clustered in hotspots, whose location is determined by the PRDM9 p...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Lesecque, Yann, Glémin, Sylvain, Lartillot, Nicolas, Mouchiroud, Dominique, Duret, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230742/
https://ncbi.nlm.nih.gov/pubmed/25393762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004790
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