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Interleukin 3-dependent survival by the Akt protein kinase

Interleukin 3 (IL-3)-dependent survival of hematopoietic cells is known to rely on the activity of multiple signaling pathways, including a pathway leading to activation of phosphoinositide 3-kinase (PI 3-kinase), and protein kinase Akt is a direct target of PI 3-kinase. We find that Akt kinase acti...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Songyang, Zhou, Baltimore, David, Cantley, Lewis C., Kaplan, David R., Franke, Thomas F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1997
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23462/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326612/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11345
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