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Bioactive and nuclease-resistant l-DNA ligand of vasopressin

In vitro selection experiments have produced nucleic acid ligands (aptamers) that bind tightly and specifically to a great variety of target biomolecules. The utility of aptamers is often limited by their vulnerability to nucleases present in biological materials. One way to circumvent this problem...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Williams, Kelly P., Liu, Xiao-Hong, Schumacher, Ton N. M., Lin, Herbert Y., Ausiello, Dennis A., Kim, Peter S., Bartel, David P.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23443/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326601/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11285
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