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A model for transition of 5'-nuclease domain of DNA polymerase I from inert to active modes.

Bacteria contain DNA polymerase I (PolI), a single polypeptide chain consisting of ∼930 residues, possessing DNA-dependent DNA polymerase, 3'-5' proofreading and 5'-3' exonuclease (also known as flap endonuclease) activities. PolI is particularly important in the processing of Okazaki fragments gene...

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Autors principals: Ping Xie, Jon R Sayers
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS ONE
Accés en línia:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0016213&type=printable
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