Phagocytosis and intracellular killing of MD-2 opsonized Gram-negative bacteria depend on TLR4 signaling

Both Toll-like receptor 4 (TLR4)– and MD-2–deficient mice succumb to otherwise nonfatal Gram-negative bacteria inocula, demonstrating the pivotal role played by these proteins in antibacterial defense in mammals. MD-2 is a soluble endogenous ligand for TLR4 and a receptor for lipopolysaccharide (LPS...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jain, Vishal, Halle, Annett, Halmen, Kristen A., Lien, Egil, Charrel-Dennis, Marie, Ram, Sanjay, Golenbock, Douglas T., Visintin, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343597/
https://ncbi.nlm.nih.gov/pubmed/18203953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-126862
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados