Downregulation of renal AQP2 water channel and NKCC2 in mice lacking the apical Na(+)-H(+) exchanger NHE3

The apical Na(+)-H(+) exchanger NHE3 plays an important role in fluid reabsorption in the proximal tubule. However, whether its deletion alters the salt and water transport in the distal nephron remains unknown. To answer these questions, wild-type (Nhe3(+/+)) and NHE3 null mice (Nhe3(−/−)) were pla...

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Detalhes bibliográficos
Main Authors: Amlal, Hassane, Ledoussal, Clara, Sheriff, Sulaiman, Shull, Gary E, Soleimani, Manoocher
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343572/
https://ncbi.nlm.nih.gov/pubmed/14500765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.053363
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