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pH-dependent and -independent effects inhibit Ca(2+)-induced Ca(2+) release during metabolic blockade in rat ventricular myocytes

We have investigated the role of changes of intracellular pH (pH(i)) in the effects of metabolic blockade (cyanide plus 2-deoxyglucose) on Ca(2+) release from the sarcoplasmic reticulum (SR) in rat ventricular myocytes. pH(i) and cell length were measured simultaneously. Metabolic blockade decreased...

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Detalhes bibliográficos
Main Authors: O'Neill, S C, Eisner, D A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2343052/
https://ncbi.nlm.nih.gov/pubmed/12766236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.042846
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