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A mechanism for the effects of caffeine on Ca2+ release during diastole and systole in isolated rat ventricular myocytes.

1. The fluorescent indicator Indo-1 was used to measure both [Ca2+]i and [caffeine]i in single ventricular myocytes. 2. Caffeine (at concentrations of 1 mM or above) produced a transient increase of resting [Ca2+]i attributed to the release of Ca2+ ions from the sarcoplasmic reticulum (SR). Simultan...

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Detalhes bibliográficos
Main Authors: O'Neill, S C, Eisner, D A
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181751/
https://ncbi.nlm.nih.gov/pubmed/2086772
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