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Interplay between SERCA and sarcolemmal Ca(2+) efflux pathways controls spontaneous release of Ca(2+) from the sarcoplasmic reticulum in rat ventricular myocytes

Waves of calcium-induced calcium release occur in a variety of cell types and have been implicated in the origin of cardiac arrhythmias. We have investigated the effects of inhibiting the SR Ca(2+)-ATPase (SERCA) with the reversible inhibitor 2′,5′-di(tert-butyl)-1,4-benzohydroquinone (TBQ) on the p...

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Detalhes bibliográficos
Main Authors: O'Neill, S C, Miller, L, Hinch, R, Eisner, D A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665077/
https://ncbi.nlm.nih.gov/pubmed/15194743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.058917
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