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Functional identification of ion binding sites at the internal end of the pore in Shaker K(+) channels
The inner end of the pore in voltage-gated K(+) channels is the site of conformational changes related to gating and contains binding sites for permeant ions and pore-blocking molecules including quaternary ammonium ions and drugs. In order to determine the location and affinity of ion binding sites...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2003
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2342912/ https://ncbi.nlm.nih.gov/pubmed/12665608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.038646 |
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