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Functional identification of ion binding sites at the internal end of the pore in Shaker K(+) channels

The inner end of the pore in voltage-gated K(+) channels is the site of conformational changes related to gating and contains binding sites for permeant ions and pore-blocking molecules including quaternary ammonium ions and drugs. In order to determine the location and affinity of ion binding sites...

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Hlavní autoři: Thompson, Jill, Begenisich, Ted
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342912/
https://ncbi.nlm.nih.gov/pubmed/12665608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.038646
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