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Crystallization and preliminary X-ray diffraction of human interleukin-7 bound to unglycosylated and glycosylated forms of its α-receptor

The interleukin-7 (IL-7) signaling pathway plays an essential role in the development, proliferation and homeostasis of T and B cells in cell-mediated immunity. Understimulation and overstimulation of the IL-7 signaling pathway leads to severe combined immunodeficiency, autoimmune reactions, heart d...

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Detalhes bibliográficos
Main Authors: Wickham, Joseph, Walsh, Scott T. R.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2339731/
https://ncbi.nlm.nih.gov/pubmed/17909291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107042807
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