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β-Catenin mutations in cell lines established from human colorectal cancers

β-catenin has functions as both an adhesion and a signaling molecule. Disruption of these functions through mutations of the β-catenin gene (CTNNB1) may be important in the development of colorectal tumors. We examined the entire coding sequence of β-catenin by reverse transcriptase–PCR (RT-PCR) and...

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Detalhes bibliográficos
Main Authors: Ilyas, M., Tomlinson, I. P. M., Rowan, A., Pignatelli, M., Bodmer, W. F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23362/
https://ncbi.nlm.nih.gov/pubmed/9294210
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