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Kinetic Mechanism of Fully Activated S6K1 Protein Kinase
S6K1 is a member of the AGC subfamily of serine-threonine protein kinases, whereby catalytic activation requires dual phosphorylation of critical residues in the conserved T-loop (Thr-229) and hydrophobic motif (Thr-389). Previously, we described production of the fully activated catalytic kinase do...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2335363/ https://ncbi.nlm.nih.gov/pubmed/18326039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800114200 |
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