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Expression, purification, crystallization and preliminary X-ray analysis of the ligand-binding domain of metabotropic glutamate receptor 7

Glutamate is the major excitatory neurotransmitter and its metabotropic glutamate receptor (mGluR) plays an important role in the central nervous system. The ligand-binding domain (LBD) of mGluR subtype 7 (mGluR7) was produced using the baculovirus expression system and purified from the culture med...

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Bibliographic Details
Main Authors: Muto, Takanori, Tsuchiya, Daisuke, Morikawa, Kosuke, Jingami, Hisato
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335145/
https://ncbi.nlm.nih.gov/pubmed/17620729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107030059
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