Site-specific unglycosylation to improve crystallization of the metabotropic glutamate receptor 3 extracellular domain

Metabotropic glutamate receptors (mGluRs) are involved in the regulation of many physiological and pathological processes in the central nervous system. The extracellular domain (ECD) of mGluR subtype 3 (mGluR3) was produced using the baculovirus expression system and purified from the culture mediu...

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Bibliographic Details
Main Authors: Muto, Takanori, Tsuchiya, Daisuke, Morikawa, Kosuke, Jingami, Hisato
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2009
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650456/
https://ncbi.nlm.nih.gov/pubmed/19255473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109002267
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