Crystal structures of autoinhibitory PDZ domain of Tamalin: implications for metabotropic glutamate receptor trafficking regulation

Metabotropic glutamate receptors (mGluRs) function as neuronal G-protein-coupled receptors and this requires efficient membrane targeting through associations with cytoplasmic proteins. However, the molecular mechanism regulating mGluR cell-surface trafficking remains unknown. We report here that mG...

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Bibliographic Details
Main Authors: Sugi, Takuma, Oyama, Takuji, Muto, Takanori, Nakanishi, Shigetada, Morikawa, Kosuke, Jingami, Hisato
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852777/
https://ncbi.nlm.nih.gov/pubmed/17396155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601651
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