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Crystallization and crystallographic analysis of yeast Sec2p, a guanine nucleotide-exchange factor for the yeast Rab GTPase Sec4p

Sec2p is a guanine nucleotide-exchange factor (GEF) for the yeast Rab GTPase Sec4p. Sec2p accelerates GDP release from Sec4p and promotes GDP–GTP exchange for Sec4p activation. In order to elucidate this nucleotide-exchange mechanism using X-ray crystallography, three constructs of native Sec2p (Sec...

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Detalhes bibliográficos
Main Authors: Sato, Yusuke, Fukai, Shuya, Nureki, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335144/
https://ncbi.nlm.nih.gov/pubmed/17620726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107027121
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