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Ypt32 recruits the Sec4p guanine nucleotide exchange factor, Sec2p, to secretory vesicles; evidence for a Rab cascade in yeast

SEC2 is an essential gene required for polarized growth of the yeast Saccharomyces cerevisiae. It encodes a protein of 759 amino acids that functions as a guanine nucleotide exchange factor for the small GTPase Sec4p, a regulator of Golgi to plasma membrane transport. Activation of Sec4p by Sec2p is...

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Detalhes bibliográficos
Main Authors: Ortiz, Darinel, Medkova, Martina, Walch-Solimena, Christiane, Novick, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174052/
https://ncbi.nlm.nih.gov/pubmed/12045183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200201003
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