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A catalytic coiled-coil: structural insights into the activation of the Rab GTPase Sec4p by Sec2p
Rab GTPases, the largest subgroup in the superfamily of Ras-like GTPases, play regulatory roles in multiple steps of intracellular vesicle trafficking. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the interconversion of the GDP-bound, or inactive, form of Rab to t...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847580/ https://ncbi.nlm.nih.gov/pubmed/17289591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.01.013 |
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