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Expression, purification and crystallization of a human tau-tubulin kinase 2 that phosphorylates tau protein
Tau-tubulin kinase 2 (TTBK2) is a Ser/Thr kinase that putatively phosphorylates residues Ser208 and Ser210 (numbered according to a 441-residue human tau isoform) in tau protein. Functional analyses revealed that a recombinant kinase domain (residues 1–331) of human TTBK2 expressed in insect cells w...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
International Union of Crystallography
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2335129/ https://ncbi.nlm.nih.gov/pubmed/17620722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107028783 |
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