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Weak correlation between sequence conservation in promoter regions and in protein-coding regions of human-mouse orthologous gene pairs

BACKGROUND: Interspecies sequence comparison is a powerful tool to extract functional or evolutionary information from the genomes of organisms. A number of studies have compared protein sequences or promoter sequences between mammals, which provided many insights into genomics. However, the correla...

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Autori principali: Chiba, Hirokazu, Yamashita, Riu, Kinoshita, Kengo, Nakai, Kenta
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335122/
https://ncbi.nlm.nih.gov/pubmed/18384671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-152
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