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Improvement of domain-level ortholog clustering by optimizing domain-specific sum-of-pairs score

BACKGROUND: Identification of ortholog groups is a crucial step in comparative analysis of multiple genomes. Although several computational methods have been developed to create ortholog groups, most of those methods do not evaluate orthology at the sub-gene level. In our method for domain-level ort...

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Autors principals: Chiba, Hirokazu, Uchiyama, Ikuo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035852/
https://ncbi.nlm.nih.gov/pubmed/24885064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-148
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