Phage display of a catalytic antibody to optimize affinity for transition-state analog binding

Catalytic antibodies have shown great promise for catalyzing a tremendously diverse set of natural and unnatural chemical transformations. However, few catalytic antibodies have efficiencies that approach those of natural enzymes. In principle, random mutagenesis procedures such as phage display cou...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Baca, Manuel, Scanlan, Thomas S., Stephenson, Robert C., Wells, James A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1997
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.19.10063
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