Phage display of a catalytic antibody to optimize affinity for transition-state analog binding
Catalytic antibodies have shown great promise for catalyzing a tremendously diverse set of natural and unnatural chemical transformations. However, few catalytic antibodies have efficiencies that approach those of natural enzymes. In principle, random mutagenesis procedures such as phage display cou...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1997
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.19.10063 |
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