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A Quantitative High-Throughput Screen Identifies Potential Epigenetic Modulators of Gene Expression
Epigenetic regulation of gene expression is essential in embryonic development and contributes to cancer pathology. We used a cell-based imaging assay that measures derepression of a silenced GFP reporter to identify novel classes of compounds involved in epigenetic regulation. This Locus Derepressi...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2330280/ https://ncbi.nlm.nih.gov/pubmed/18211814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.12.028 |
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