Загрузка...

C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity

The p53 family is known as a family of transcription factors with functions in tumor suppression and development. Whereas the central DNA-binding domain is highly conserved among the three family members p53, p63 and p73, the C-terminal domains (CTDs) are diverse and subject to alternative splicing...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Sauer, Markus, Bretz, Anne Catherine, Beinoraviciute-Kellner, Rasa, Beitzinger, Michaela, Burek, Christof, Rosenwald, Andreas, Harms, Gregory S., Stiewe, Thorsten
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330244/
https://ncbi.nlm.nih.gov/pubmed/18267967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn044
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!