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Expression, purification, crystallization and preliminary X-ray diffraction analysis of the VP8* sialic acid-binding domain of porcine rotavirus strain OSU

The rotavirus outer capsid spike protein VP4 is utilized in the process of rotavirus attachment to and membrane penetration of host cells. VP4 is cleaved by trypsin into two domains: VP8* and VP5*. The VP8* domain is implicated in initial interaction with sialic acid-containing cell-surface carbohyd...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Yang-De, Li, Hao, Liu, Hui, Pan, Yi-Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330132/
https://ncbi.nlm.nih.gov/pubmed/17277447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106055849
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