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A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes

Synthesis of mouse metallothionein (MT)-I and MT-II is transcriptionally induced by the synthetic glucocorticoid, dexamethasone (DEX) or both in vivo as well as in numerous cell lines. However, the location(s) of a glucocorticoid response element (GRE) has not been described. The observation that a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kelly, Edward J., Sandgren, Eric P., Brinster, Ralph L., Palmiter, Richard D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23299/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294160/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.19.10045
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