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Development of Diabesity in Mice with Neuronal Deletion of Shp2 Tyrosine Phosphatase

Obesity and diabetes, termed “diabesity,” are serious health problems that are increasing in frequency. However, the molecular mechanisms and neuronal regulation of these metabolic disorders are not fully understood. We show here that Shp2, a widely expressed Src homology 2-containing Tyr phosphatas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Krajewska, Maryla, Banares, Steven, Zhang, Eric E., Huang, Xianshu, Scadeng, Miriam, Jhala, Ulupi S., Feng, Gen-Sheng, Krajewski, Stan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329840/
https://ncbi.nlm.nih.gov/pubmed/18403587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070594
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