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Development of Diabesity in Mice with Neuronal Deletion of Shp2 Tyrosine Phosphatase
Obesity and diabetes, termed “diabesity,” are serious health problems that are increasing in frequency. However, the molecular mechanisms and neuronal regulation of these metabolic disorders are not fully understood. We show here that Shp2, a widely expressed Src homology 2-containing Tyr phosphatas...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Investigative Pathology
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2329840/ https://ncbi.nlm.nih.gov/pubmed/18403587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070594 |
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