A Novel Mechanism for CCR4 in the Regulation of Macrophage Activation in Bleomycin-Induced Pulmonary Fibrosis

Macrophage polarization into M1 or M2 phenotypes dictates the nature, duration, and severity of an inflammatory response. The objective of this study was to examine the role of CC chemokine receptor 4 (CCR4) in macrophage polarization during pulmonary oxidative injury in wild-type [WT (CCR4(+/+))] a...

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Detalhes bibliográficos
Main Authors: Trujillo, Glenda, O’Connor, Erica C., Kunkel, Steven L., Hogaboam, Cory M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329831/
https://ncbi.nlm.nih.gov/pubmed/18403600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070832
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