A Novel Mechanism for CCR4 in the Regulation of Macrophage Activation in Bleomycin-Induced Pulmonary Fibrosis

Macrophage polarization into M1 or M2 phenotypes dictates the nature, duration, and severity of an inflammatory response. The objective of this study was to examine the role of CC chemokine receptor 4 (CCR4) in macrophage polarization during pulmonary oxidative injury in wild-type [WT (CCR4(+/+))] a...

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Bibliografski detalji
Glavni autori: Trujillo, Glenda, O’Connor, Erica C., Kunkel, Steven L., Hogaboam, Cory M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2008
Teme:
Regular Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329831/
https://ncbi.nlm.nih.gov/pubmed/18403600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070832
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