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Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome
To determine whether adipocyte storage capacity influences the onset and severity of type 2 diabetes and other components of the metabolic syndrome, we made normal and db/db mice resistant to obesity by overexpressing leptin receptor-b on the aP2-Lepr-b promoter. On a 4% diet, these mice have no phe...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2329698/ https://ncbi.nlm.nih.gov/pubmed/18413598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801981105 |
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