Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK Activation

BACKGROUND: DNA damage such as double-stranded DNA breaks (DSBs) has been reported to stimulate mitochondrial biogenesis. However, the underlying mechanism is poorly understood. The major player in response to DSBs is ATM (ataxia telangiectasia mutated). Upon sensing DSBs, ATM is activated through a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fu, Xuan, Wan, Shan, Lyu, Yi Lisa, Liu, Leroy F., Qi, Haiyan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2008
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329593/
https://ncbi.nlm.nih.gov/pubmed/18431490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002009
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